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Cattle drive casserole 2026 05 18 150931 819x1024

Cattle Drive Casserole

A hearty casserole packed with flavors and protein, perfect for family gatherings.
Prep Time 20 minutes
Cook Time 38 minutes
Total Time 58 minutes
Course Dinner, Main Course
Cuisine American
Servings 8 servings
Calories 400 kcal

Ingredients
  

Meat and Vegetables

  • 1.5 pounds Lean Ground Beef
  • 1 piece Red Bell Pepper, seeded and chopped
  • 1 piece Yellow Onion, chopped
  • 1 ounce Taco Seasoning Mix

Biscuit Base

  • 2.5 cups Biscuit Mix, like Bisquick
  • 1 cup Water
  • 1 can Cooking Spray, like Pam

Creamy Layer

  • 0.5 cup Sour Cream
  • 0.5 cup Mayonnaise
  • 4 ounces Diced Green Chiles, drained
  • 1.5 cups Cheddar Cheese, Fiesta Blend, shredded
  • 1 teaspoon Garlic Powder

Final Topping

  • 0.5 cup Salsa, mild

Instructions
 

Preparation

  • Preheat the oven to 350℉.
  • In a skillet over medium-high heat, cook the ground beef until no longer pink, then drain excess fat.
  • In a mixing bowl, combine biscuit mix and water; mix thoroughly and press into a greased casserole dish.
  • Bake the biscuit layer for 5-8 minutes, until set and lightly golden, then set aside.

Cooking

  • Add chopped onions and red bell pepper to the cooked ground beef, and stir for about 4 minutes.
  • Mix in the taco seasoning and remove from heat.

Assembly

  • Spread the ground beef mixture over the baked biscuit layer.
  • In a bowl, combine sour cream, mayonnaise, green chiles, ¾ cup cheese, and garlic powder; mix until smooth and spread over the beef layer.
  • Dollop salsa over the sour cream layer and sprinkle with remaining cheese.

Baking

  • Bake in the oven for 30 minutes or until hot and bubbly.

Notes

You can add corn or black beans for extra flavor. For a spicier kick, use hot salsa or jalapeños. This dish can be prepared ahead of time to make serving easier.
Keyword Casserole, Cattle Drive Casserole, Comfort Food, Easy Dinner, family meal